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DNA Purification and Cleanup

The Agencourt line of reagent systems, accessories, and software methods coupled with Beckman Coulter automation, create an unparalleled alignment of automation proficiency. The reagents are based on Solid Phase Reversible Immobilization (SPRI) paramagnetic bead-based technology, which is ideal for automating on Biomek Laboratory Automation Workstations. The end result is faster throughput and higher quality data.

SPRI is a patented, high performance nucleic acid purification technology developed at the Whitehead Institute (Hawkins, et. al., Nucleic Acids Res. 1995 (23): 4742-4743). Targeted nucleic acids are immobilized onto paramagnetic microparticles using specific buffer conditions. Contaminants are easily removed without the need for centrifugation or filtration, creating a streamlined, scalable and automation-compatible format.

DNA Purification and Cleanup Systems

Agencourt AMPure XP System - PCR Purification
Agencourt CleanSEQ System - Dye Terminator Removal
Agencourt CosMCPrep System - High/Low Copy Fosmid and BAC Purification
Agencourt DNAdvance System - Nucleic Acid Isolation from Mammalian Tissue
Agencourt Genfind v2 System - Genomic DNA Isolation from Blood

† The PCR process is covered by patents owned by Roche Molecular Systems, Inc.,
and F. Hoffman-La Roche, Ltd.
Beckman Coulter, the stylized logo, Agencourt, AMPure, Biomek, CleanSEQ, CosMCPrep, DNAdvance, FormaPure, Genfind, RNAClean, RNAdvance and SPRI are registered trademarks of Beckman Coulter, Inc.